Advice to a young scientist by Peter Medawar (Basic Books). The titan of 20th century molecular medicine gives well-meaning and funny (in the British sense) advice on (from the chapter headings): How do I tell if I am cut out to be a scientific research worker? - What shall I do research on? - How can I equip myself to be a scientist or a better one? - Women in science - Aspects of scientific life and manners - Of younger and older scientists - Presentations - Experiment and discovery - Prizes and rewards - The scientific process. Some details of the 25-year old book feel out of date now but it still is an excellent companion up to your first faculty position. See the following quote: "A novice must stick it out until he discovers whether the rewards and compensations of the scientific life are for him comensurate with the disappointments and the toil; but if once a scientist experiences the exhilaration of discovery [...] then he is hooked, and no other kind of life will do."